RUNX3 (NM_001031680) Human Recombinant Protein

CAT#: TP760558

Purified recombinant protein of Human runt-related transcription factor 3 (RUNX3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length RUNX3
• Tag: N-His
• Predicted MW: 45.7 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris,8M Urea,pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001026850
• Locus ID: 864
• UniProt ID: Q13761, A0A024RAH4
• Cytogenetics: 1p36.11
• Refseq Size: 4340
• Refseq ORF: 1287
• Synonyms: AML2; CBFA3; PEBP2aC
• Summary: 'This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]'
• Protein Families: Transcription Factors