MED28 (NM_025205) Human Recombinant Protein

CAT#: TP760745

Purified recombinant protein of Human mediator complex subunit 28 (MED28), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length MED28
Tag N-His
Predicted MW 19.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_079481
Locus ID 80306
UniProt ID Q9H204
Cytogenetics 4p15.32
Refseq Size 1363
Refseq ORF 534
Synonyms 1500003D12Rik; EG1; magicin
Summary Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. [UniProtKB/Swiss-Prot Function]
Protein Families Transcription Factors

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