IL28A (IFNL2) (NM_172138) Human Recombinant Protein

CAT#: TP760751

Purified recombinant protein of Human interleukin 28A (interferon, lambda 2) (IL28A), full length, with N-terminal HIS tag, expressed in E. coli, 50ug


  View other "IFNL2" proteins (3)

USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length IL28A
Tag N-His
Predicted MW 22.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_742150
Locus ID 282616
UniProt ID Q8IZJ0
Cytogenetics 19q13.2
Refseq Size 734
Refseq ORF 600
Synonyms IL-28A; IL28A
Summary This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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