C12orf32 (NM_031465) Human Recombinant Protein

CAT#: TP760852

Purified recombinant protein of Human chromosome 12 open reading frame 32 (C12orf32), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Tag: N-His
• Predicted MW: 26.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Reference Data

• RefSeq: NP_113653
• Locus ID: 83695
• Cytogenetics: 12p13.33
• Refseq Size: 1872
• Refseq ORF: 714
• Synonyms: chromosome 12 open reading frame 32; HKMT1188; HKMT1188, MGC13204; MGC13204
• Summary: Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation. [UniProtKB/Swiss-Prot Function]