ATG16L1 (NM_198890) Human Recombinant Protein

CAT#: TP761243

Purified recombinant protein of Human ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length ATG16L1
Tag N-His
Predicted MW 49.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_942593
Locus ID 55054
UniProt ID Q676U5
Cytogenetics 2q37.1
Refseq ORF 1332
Synonyms APG16L; ATG16A; ATG16L; IBD10; WDR30
Summary The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

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