CACNB2 (NM_000724) Human Recombinant Protein

CAT#: TP761246

Purified recombinant protein of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length CACNB2
• Tag: N-His
• Predicted MW: 68 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000715
• Locus ID: 783
• UniProt ID: Q08289, Q59H42
• Cytogenetics: 10p12.33-p12.31
• Refseq Size: 3721
• Refseq ORF: 1815
• Synonyms: CAB2; CACNLB2; CAVB2; MYSB
• Summary: 'This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]'
• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway