RNF144 (RNF144A) (NM_014746) Human Recombinant Protein
CAT#: TP761319
Purified recombinant protein of Human ring finger protein 144A (RNF144A), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Other products for "RNF144A"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length RNF144A
|
Tag | N-GST and C-His |
Predicted MW | 58.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_055561 |
Locus ID | 9781 |
UniProt ID | P50876 |
Cytogenetics | 2p25.1 |
Refseq Size | 5755 |
Refseq ORF | 876 |
Synonyms | hUIP4; RNF144; UBCE7IP4 |
Summary | This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017] |
Protein Families | Druggable Genome, Transmembrane |
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