ULBP2 (NM_025217) Human Recombinant Protein

CAT#: TP761323

Purified recombinant protein of Human UL16 binding protein 2 (ULBP2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length ULBP2
• Tag: N-GST and C-His
• Predicted MW: 53.2 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_079493
• Locus ID: 80328
• UniProt ID: Q9BZM5
• Cytogenetics: 6q25.1
• Refseq Size: 1362
• Refseq ORF: 738
• Synonyms: ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; RAET1L
• Summary: This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity