DSCR1L1 (RCAN2) (NM_005822) Human Recombinant Protein

CAT#: TP761325

Purified recombinant protein of Human regulator of calcineurin 2 (RCAN2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length RCAN2
• Tag: N-GST and C-His
• Predicted MW: 51 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_005813
• Locus ID: 10231
• UniProt ID: Q14206, B2R612
• Cytogenetics: 6p12.3
• Refseq Size: 3438
• Refseq ORF: 1449
• Synonyms: CSP2; DSCR1L1; MCIP2; RCN2; ZAKI-4; ZAKI4
• Summary: This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]