n-Myc (MYCN) (NM_005378) Human Recombinant Protein

CAT#: TP761572

Purified recombinant protein of Human v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MycN), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length MYCN
• Tag: N-GST and C-His
• Predicted MW: 77.4 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1%Sarkosyl.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_005369
• Locus ID: 4613
• UniProt ID: P04198
• Cytogenetics: 2p24.3
• Refseq Size: 2736
• Refseq ORF: 1392
• Synonyms: bHLHe37; MODED; N-myc; NMYC; ODED
• Summary: 'This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]'
• Protein Families: Druggable Genome, Transcription Factors