Histone H2A.X (H2AFX) (NM_002105) Human Recombinant Protein

CAT#: TP761594

Purified recombinant protein of Human H2A histone family, member X (H2AFX), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length H2AFX
Tag N-GST and C-His
Predicted MW 43 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1%Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002096
Locus ID 3014
UniProt ID P16104
Cytogenetics 11q23.3
Refseq Size 1651
Refseq ORF 429
Synonyms H2A.X; H2A/X; H2AX
Summary 'Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]'
Protein Families Druggable Genome
Protein Pathways Systemic lupus erythematosus

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