MYH (MUTYH) (NM_001048174) Human Recombinant Protein
CAT#: TP761664
Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH), transcript variant beta3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length MUTYH
|
Tag | N-His |
Predicted MW | 57.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0,8M Urea. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001041639 |
Locus ID | 4595 |
UniProt ID | Q9UIF7 |
Cytogenetics | 1p34.1 |
Refseq Size | 1710 |
Refseq ORF | 1563 |
Synonyms | MYH |
Summary | 'This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]' |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Base excision repair |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC420769 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC420770 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC420771 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC425817 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC426953 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY420769 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma2 |
USD 605.00 |
|
LY420770 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma3 |
USD 605.00 |
|
LY420771 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant beta3 |
USD 396.00 |
|
LY425817 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma3 |
USD 396.00 |
|
LY426953 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant alpha5 |
USD 396.00 |
|
TP760878 | Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH / MYH), transcript variant alpha1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug |
USD 215.00 |
|
TP761725 | Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH), transcript variant gamma3, full length, with N-terminal His tag, expressed in E. coli, 50ug |
USD 215.00 |
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