APLP1 (NM_001024807) Human Recombinant Protein
CAT#: TP761802
Purified recombinant protein of Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Other products for "APLP1"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length APLP1
|
Tag | N-GST and C-His |
Predicted MW | 96.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0,8M Urea. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001019978 |
Locus ID | 333 |
UniProt ID | P51693 |
Cytogenetics | 19q13.12 |
Refseq Size | 2450 |
Refseq ORF | 1188 |
Synonyms | APLP |
Summary | 'This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome, Transmembrane |
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