TREX1 (NM_016381) Human Recombinant Protein

CAT#: TP761837

Purified recombinant protein of Human three prime repair exonuclease 1 (TREX1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Tag N-GST and C-His
Predicted MW 66.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0,8M Urea.
Reference Data
RefSeq NP_057465
Locus ID 11277
Cytogenetics 3p21.31
Refseq Size 2216
Refseq ORF 1107
Synonyms AGS1; CRV; DRN3; HERNS
Summary This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytosolic DNA-sensing pathway

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