TRIF (TICAM1) (NM_182919) Human Recombinant Protein
CAT#: TP761852
Purified recombinant protein of Human toll-like receptor adaptor molecule 1 (TICAM1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Other products for "TICAM1"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length TICAM1
|
Tag | N-GST and C-His |
Predicted MW | 104.2 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0,8M Urea. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_891549 |
Locus ID | 148022 |
UniProt ID | Q8IUC6 |
Cytogenetics | 19p13.3 |
Refseq Size | 2460 |
Refseq ORF | 2136 |
Synonyms | IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF |
Summary | This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012] |
Protein Families | Druggable Genome |
Protein Pathways | Toll-like receptor signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
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