CDC42 binding protein kinase alpha (CDC42BPA) (NM_014826) Human Recombinant Protein

CAT#: TP761915

Purified recombinant protein of Human CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA), transcript variant A, Ser1419-Pro1638, with N-terminal HIS tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Ser1419-Pro1638) of CDC42BPA
Tag N-His
Predicted MW 30 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0,150 mM NaCl, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_055641
Locus ID 8476
UniProt ID Q5VT25
Cytogenetics 1q42.13
Refseq Size 7776
Refseq ORF 5262
Synonyms MRCK; MRCKA; PK428
Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]
Protein Families Druggable Genome, Protein Kinase

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