KCNH1 (NM_172362) Human Recombinant Protein

CAT#: TP761931

Purified recombinant protein of Human potassium voltage-gated channel, subfamily H (eag-related), member 1 (KCNH1), transcript variant 1,Asp878-Ser981, with N-terminal His-ABP tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Asp878-Ser981) of KCNH1
• Tag: N-His-ABP
• Predicted MW: 26.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0,150 mM NaCl, 10% glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_758872
• Locus ID: 3756
• UniProt ID: O95259
• Cytogenetics: 1q32.2
• Refseq Size: 3208
• Refseq ORF: 2967
• Synonyms: EAG; EAG1; h-eag; hEAG1; Kv10.1; TMBTS; ZLS1
• Summary: 'Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane