TREM2 (NM_018965) Human Recombinant Protein

CAT#: TP761948

Purified recombinant protein of Human triggering receptor expressed on myeloid cells 2 (TREM2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding full-length of TREM2
Tag N-GST and C-His
Predicted MW 51.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_061838
Locus ID 54209
UniProt ID Q9NZC2, Q5TCX1
Cytogenetics 6p21.1
Refseq Size 1041
Refseq ORF 690
Synonyms PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
Summary This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
Protein Families Druggable Genome, Secreted Protein, Transmembrane

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