TYK2 (NM_003331) Human Recombinant Protein
CAT#: TP761982
Purified recombinant protein of Human tyrosine kinase 2 (TYK2),Arg240-Val387, with N-terminal His-ABP tag, expressed in E. coli, 50ug
Other products for "TYK2"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Arg240-Val387)of TYK2
|
Tag | N-His-ABP |
Predicted MW | 31.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_003322 |
Locus ID | 7297 |
UniProt ID | P29597, A0A024R7E4 |
Cytogenetics | 19p13.2 |
Refseq Size | 4262 |
Refseq ORF | 3561 |
Synonyms | IMD35; JTK1 |
Summary | 'This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. [provided by RefSeq, Jul 2020]' |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Jak-STAT signaling pathway |
Documents
FAQs |
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Recombinant Protein Resources |
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