TYK2 (NM_003331) Human Recombinant Protein

CAT#: TP761982

Purified recombinant protein of Human tyrosine kinase 2 (TYK2),Arg240-Val387, with N-terminal His-ABP tag, expressed in E. coli, 50ug


USD 215.00

In Stock*

Size
    • 50 ug

Product Images

Other products for "TYK2"

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Arg240-Val387)of TYK2
Tag N-His-ABP
Predicted MW 31.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003322
Locus ID 7297
UniProt ID P29597, A0A024R7E4
Cytogenetics 19p13.2
Refseq Size 4262
Refseq ORF 3561
Synonyms IMD35; JTK1
Summary 'This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. [provided by RefSeq, Jul 2020]'
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Jak-STAT signaling pathway

Documents

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.