EIF4EBP1 (NM_004095) Human Recombinant Protein
CAT#: TP762017
Purified recombinant protein of Human eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1),Ser2-Ile118, with N-terminal His tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Ser2-Ile118) of EIF4EBP1
|
Tag | N-His |
Predicted MW | 12.4 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_004086 |
Locus ID | 1978 |
UniProt ID | Q13541 |
Cytogenetics | 8p11.23 |
Refseq Size | 895 |
Refseq ORF | 354 |
Synonyms | 4E-BP1; 4EBP1; BP-1; PHAS-I |
Summary | 'This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]' |
Protein Pathways | Acute myeloid leukemia, ErbB signaling pathway, Insulin signaling pathway, mTOR signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401322 | EIF4EBP1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY401322 | Transient overexpression lysate of eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) |
USD 396.00 |
|
TP720177 | Recombinant protein of human eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) |
USD 330.00 |
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