LNX1 (NM_032622) Human Recombinant Protein

CAT#: TP762034

Purified recombinant protein of Human ligand of numb-protein X 1 (LNX1), transcript variant 2,Met260-Val528, with N-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Met260-Val528) of LNX1
• Tag: N-His
• Predicted MW: 29.7 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_116011
• Locus ID: 84708
• UniProt ID: Q8TBB1
• Cytogenetics: 4q12
• Refseq Size: 2930
• Refseq ORF: 1896
• Synonyms: LNX; MPDZ; PDZRN2
• Summary: This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome