SENP7 (NM_020654) Human Recombinant Protein

CAT#: TP762052

Purified recombinant protein of Human SUMO1/sentrin specific peptidase 7 (SENP7), transcript variant 1,Met1-Lys367, with N-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Met1-Lys367) of SENP7
Tag N-His
Predicted MW 41.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_065705
Locus ID 57337
UniProt ID Q9BQF6
Cytogenetics 3q12.3
Refseq Size 5018
Refseq ORF 3150
Synonyms KIAA1707; MGC157730
Summary The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]). [supplied by OMIM, Jun 2009]
Protein Families Druggable Genome, Protease

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