Kv2.1 (KCNB1) (NM_004975) Human Recombinant Protein

CAT#: TP762055

Purified recombinant protein of Human potassium voltage-gated channel, Shab-related subfamily, member 1 (KCNB1),Gln509-Cys813, with N-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Gln509-Cys813) of KCNB1
Tag N-His
Predicted MW 32.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_004966
Locus ID 3745
UniProt ID Q14721
Cytogenetics 20q13.13
Refseq Size 3756
Refseq ORF 2574
Synonyms DRK1; Kv2.1
Summary 'Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane
Protein Pathways Taste transduction

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