AICDA (NM_020661) Human Recombinant Protein

CAT#: TP762070

Purified recombinant protein of Human activation-induced cytidine deaminase (AICDA),full length, with N-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length AICDA
• Tag: N-His
• Predicted MW: 23.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_065712
• Locus ID: 57379
• UniProt ID: Q9GZX7, Q546Y9, Q7Z599
• Cytogenetics: 12p13.31
• Refseq Size: 2794
• Refseq ORF: 594
• Synonyms: AID; ARP2; CDA2; HEL-S-284; HIGM2
• Summary: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]
• Protein Families: Druggable Genome
• Protein Pathways: Primary immunodeficiency