KCNN4 (NM_002250) Human Recombinant Protein

CAT#: TP762082

Purified recombinant protein of Human potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (KCNN4),Phe301-Lys360, with N-terminal His-ABP tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Phe301-Lys360) of KCNN4
Tag N-His-ABP
Predicted MW 22.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002241
Locus ID 3783
UniProt ID O15554
Cytogenetics 19q13.31
Refseq Size 2240
Refseq ORF 1281
Synonyms DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; KCa3.1; KCA4; SK4
Summary 'The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane

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