CYP1B1 (NM_000104) Human Recombinant Protein

CAT#: TP762099

Purified recombinant protein of Human cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1),Leu40-Ala305, with N-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Leu40-Ala305) of CYP1B1
Tag N-His
Predicted MW 30 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000095
Locus ID 1545
UniProt ID Q16678, Q53TK1
Cytogenetics 2p22.2
Refseq Size 5160
Refseq ORF 1629
Synonyms ASGD6; CP1B; CYPIB1; GLC3A; P4501B1
Summary 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome, P450
Protein Pathways Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism

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