PLK4 (NM_014264) Human Recombinant Protein

CAT#: TP762134

Purified recombinant protein of Human polo-like kinase 4 (PLK4), transcript variant 1,Phe307-Ser612, with N-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Phe307-Ser612) of PLK4
• Tag: N-His
• Predicted MW: 34.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_055079
• Locus ID: 10733
• UniProt ID: O00444
• Cytogenetics: 4q28.1
• Refseq Size: 3870
• Refseq ORF: 2910
• Synonyms: MCCRP2; SAK; STK18
• Summary: This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
• Protein Families: Druggable Genome, Protein Kinase