TRIB3 (NM_021158) Human Recombinant Protein

CAT#: TP762145

Purified recombinant protein of Human tribbles homolog 3 (Drosophila) (TRIB3),Met1-Leu200, with N-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Met1-Leu200) of TRIB3
Tag N-His
Predicted MW 22.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_066981
Locus ID 57761
UniProt ID Q96RU7
Cytogenetics 20p13
Refseq Size 2469
Refseq ORF 1074
Synonyms C20orf97; NIPK; SINK; SKIP3; TRB3
Summary The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Protein Families Druggable Genome, Protein Kinase, Transcription Factors

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