MMP15 (NM_002428) Human Recombinant Protein

CAT#: TP762159

Purified recombinant protein of Human matrix metallopeptidase 15 (membrane-inserted) (MMP15), Gly304-Val614, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein MMP15 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Gly304-Val614) of MMP15
• Tag: N-His
• Predicted MW: 35.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002419
• Locus ID: 4324
• UniProt ID: P51511, A0A024R6U8
• Cytogenetics: 16q21
• Refseq Size: 4456
• Refseq ORF: 2007
• Synonyms: MMP-15; MT2-MMP; MT2MMP; MTMMP2; SMCP-2
• Summary: 'This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016]'
• Protein Families: Druggable Genome, Protease, Transmembrane