HIF 2 alpha (EPAS1) (NM_001430) Human Recombinant Protein

CAT#: TP762188

Purified recombinant protein of Human endothelial PAS domain protein 1 (EPAS1), Leu584-end, with N-terminal His tag, expressed in E.coli, 50ug


  View other "EPAS1" proteins (2)

USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Leu584-end) of EPAS1
Tag N-His
Predicted MW 31.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001421
Locus ID 2034
UniProt ID Q99814, B3KW07
Cytogenetics 2p21
Refseq Size 5184
Refseq ORF 2610
Synonyms bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
Summary 'This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]'
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma

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