NSD3 (WHSC1L1) (NM_017778) Human Recombinant Protein

CAT#: TP762239

Purified recombinant protein of Human Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1), transcript variant short, Asn427-Ser566, with N-terminal His-ABP tag, expressed in E.coli, 50ug


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USD 205.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Asn427-Ser566) of WHSC1L1
Tag N-His ABP
Predicted MW 30.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_060248
Locus ID 54904
UniProt ID Q9BZ95
Cytogenetics 8p11.23
Refseq Size 3995
Refseq ORF 1935
Synonyms KMT3F; KMT3G; pp14328; WHISTLE; WHSC1L1
Summary This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Lysine degradation

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