BORIS (CTCFL) (NM_080618) Human Recombinant Protein

CAT#: TP762263

Purified recombinant protein of Human CCCTC-binding factor (zinc finger protein)-like (CTCFL), Glu282-Thr435, with N-terminal His tag, expressed in E.coli, 50ug


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USD 205.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Glu282-Thr435) of CTCFL
Tag N-His
Predicted MW 18.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_542185
Locus ID 140690
UniProt ID Q8NI51
Cytogenetics 20q13.31
Refseq Size 3493
Refseq ORF 1989
Synonyms BORIS; CT27; CTCF-T; dJ579F20.2; HMGB1L1
Summary CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Protein Families Transcription Factors

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