TGF beta Receptor III (TGFBR3) (NM_003243) Human Recombinant Protein

CAT#: TP762270

Purified recombinant protein of Human transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, Gly531-Pro777, with N-terminal His tag, expressed in E.coli, 50ug


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USD 205.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Gly531-Pro777) of TGFBR3
Tag N-His
Predicted MW 27.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003234
Locus ID 7049
UniProt ID Q03167
Cytogenetics 1p22.1
Refseq Size 4199
Refseq ORF 2553
Synonyms betaglycan; BGCAN
Summary 'This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]'
Protein Families Druggable Genome, Secreted Protein, Transmembrane

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