Cyclin T2 (CCNT2) (NM_001241) Human Recombinant Protein

CAT#: TP762273

Purified recombinant protein of Human cyclin T2 (CCNT2), transcript variant a, Ala7-Ala263, with N-terminal His tag, expressed in E.coli, 50ug


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USD 205.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Ala7-Ala263) of CCNT2
Tag N-His
Predicted MW 29.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001232
Locus ID 905
UniProt ID O60583, B4DH21
Cytogenetics 2q21.3
Refseq Size 6822
Refseq ORF 1989
Synonyms CYCT2
Summary 'The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]'
Protein Families Druggable Genome, Transcription Factors

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