CD61 (ITGB3) (NM_000212) Human Recombinant Protein

CAT#: TP762346

Purified recombinant protein of Human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3), Ser536-Asp718, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein CD61 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Ser536-Asp718) of CD61
• Tag: N-His
• Predicted MW: 20.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000203
• Locus ID: 3690
• UniProt ID: P05106
• Cytogenetics: 17q21.32
• Refseq Size: 4894
• Refseq ORF: 2364
• Synonyms: BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT
• Summary: 'The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton