TdT (DNTT) (NM_001017520) Human Recombinant Protein
CAT#: TP762363
Purified recombinant protein of Human deoxynucleotidyltransferase, terminal (DNTT), transcript variant 2, Met1-Thr160, with N-terminal His tag, expressed in E.coli, 50ug
Other products for "DNTT"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Met1-Thr160) of TDT
|
Tag | N-His |
Predicted MW | 18.0 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001017520 |
Locus ID | 1791 |
UniProt ID | P04053 |
Cytogenetics | 10q24.1 |
Refseq Size | 2068 |
Refseq ORF | 1527 |
Synonyms | TDT |
Summary | 'This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]' |
Protein Pathways | Hematopoietic cell lineage, Non-homologous end-joining |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.