PAH (NM_000277) Human Recombinant Protein

CAT#: TP762451

Purified recombinant protein of Human phenylalanine hydroxylase (PAH), full length, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein PAH was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of PAH
• Tag: N-His
• Predicted MW: 51.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000268
• Locus ID: 5053
• UniProt ID: P00439, A0A024RBG4
• Cytogenetics: 12q23.2
• Refseq Size: 2680
• Refseq ORF: 1356
• Synonyms: PH; PKU; PKU1
• Summary: 'This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]'
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Phenylalanine, tyrosine and tryptophan biosynthesis, Phenylalanine metabolism