CERK (NM_022766) Human Recombinant Protein

CAT#: TP762486

Purified recombinant protein of Human ceramide kinase (CERK), full length, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein CERK was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of CERK
• Tag: N-His
• Predicted MW: 60.0 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_073603
• Locus ID: 64781
• UniProt ID: Q8TCT0, A0A024R4U8
• Cytogenetics: 22q13.31
• Refseq Size: 4445
• Refseq ORF: 1611
• Synonyms: dA59H18.2; dA59H18.3; hCERK; LK4
• Summary: CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]). [supplied by OMIM, Mar 2008]
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism