HIF3 alpha (HIF3A) (NM_152795) Human Recombinant Protein

CAT#: TP762617

Purified recombinant protein of Human hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 3, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug


USD 261.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region full length of HIF3A
Tag N-GST and C-HIS
Predicted MW 72.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0, 8M Urea
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_690008
Locus ID 64344
UniProt ID Q9Y2N7
Cytogenetics 19q13.32
Refseq Size 5850
Refseq ORF 2007
Synonyms bHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
Summary The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.