Glycoprotein VI (GP6) (NM_016363) Human Recombinant Protein
CAT#: TP762625
Purified recombinant protein of Human glycoprotein VI (platelet) (GP6), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug
Other products for "GP6"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region full length of GP6
|
Tag | N-GST and C-HIS |
Predicted MW | 36.7 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 8M Urea |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_057447 |
Locus ID | 51206 |
UniProt ID | Q9HCN6 |
Cytogenetics | 19q13.42 |
Refseq Size | 2263 |
Refseq ORF | 1017 |
Synonyms | BDPLT11; GPIV; GPVI |
Summary | This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ECM-receptor interaction |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
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