Glycoprotein VI (GP6) (NM_016363) Human Recombinant Protein

CAT#: TP762625

Purified recombinant protein of Human glycoprotein VI (platelet) (GP6), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug


USD 261.00

2 Weeks*

Size
    • 50 ug

Product Images

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region full length of GP6
Tag N-GST and C-HIS
Predicted MW 36.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0, 8M Urea
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_057447
Locus ID 51206
UniProt ID Q9HCN6
Cytogenetics 19q13.42
Refseq Size 2263
Refseq ORF 1017
Synonyms BDPLT11; GPIV; GPVI
Summary This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Protein Families Druggable Genome, Transmembrane
Protein Pathways ECM-receptor interaction

Documents

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.