OMA1 (NM_145243) Human Recombinant Protein

CAT#: TP762640

Purified recombinant protein of Human OMA1 homolog, zinc metallopeptidase (S.cerevisiae) (OMA1), full length, with N-GST and C-His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein OMA1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of OMA1
• Tag: N-GST and C-HIS
• Predicted MW: 88.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_660286
• Locus ID: 115209
• UniProt ID: Q96E52
• Cytogenetics: 1p32.2-p32.1
• Refseq Size: 1928
• Refseq ORF: 1572
• Synonyms: 2010001O09Rik; DAB1; MPRP-1; MPRP1; peptidase; YKR087C; ZMPOMA1
• Summary: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome, Protease, Transmembrane