RSPO1 (NM_001038633) Human Recombinant Protein

CAT#: TP762643

Purified recombinant protein of Human R-spondin homolog (Xenopus laevis) (RSPO1), full length, with N-GST and C-His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein RSPO1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of RSPO1
• Tag: N-GST and C-HIS
• Predicted MW: 57.0 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001033722
• Locus ID: 284654
• UniProt ID: Q2MKA7
• Cytogenetics: 1p34.3
• Refseq Size: 2995
• Refseq ORF: 789
• Synonyms: CRISTIN3; RSPO
• Summary: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
• Protein Families: Secreted Protein