XPD (ERCC2) (NM_000400) Human Recombinant Protein
CAT#: TP762657
Purified recombinant protein of Human excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1, full length, with N-GST and C-His tag, expressed in E.coli, 50ug
Other products for "ERCC2"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region full length of ERCC2
|
Tag | N-GST and C-HIS |
Predicted MW | 114.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 8M Urea |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000391 |
Locus ID | 2068 |
UniProt ID | P18074 |
Cytogenetics | 19q13.32 |
Refseq Size | 2355 |
Refseq ORF | 2280 |
Synonyms | COFS2; EM9; TFIIH; TTD; TTD1; XPD |
Summary | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Nucleotide excision repair |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
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