ANKRD32 (SLF1) (NM_032290) Human Recombinant Protein

CAT#: TP762694

Purified recombinant protein of Human ankyrin repeat domain 32 (ANKRD32), full length, with N-GST and C-His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein ANKRD32 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of ANKRD32
• Tag: N-GST and C-HIS
• Predicted MW: 75.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_115666
• Locus ID: 84250
• UniProt ID: Q9BQI6, I6L9F1
• Cytogenetics: 5q15
• Refseq Size: 3813
• Refseq ORF: 1266
• Synonyms: ANKRD32; BRCTD1; BRCTx
• Summary: Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).[UniProtKB/Swiss-Prot Function]