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- MAP2K1 (120)
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Reactivities
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Knockout (KO) Validation
Families
- Druggable Genome (5937)
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- Stem cell relevant signaling - Wnt Signaling pathway (12)
Pathways
- Metabolic pathways (1302)
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- Jak-STAT signaling pathway (216)
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- Adherens junction (143)
- Pyrimidine metabolism (141)
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- mTOR signaling pathway (132)
- Adipocytokine signaling pathway (129)
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- Epithelial cell signaling in Helicobacter pylori infection (120)
- Glycerolipid metabolism (108)
- Tyrosine metabolism (108)
- Arginine and proline metabolism (105)
- Cytokine-cytokine receptor interaction (105)
- NOD-like receptor signaling pathway (105)
- Nucleotide excision repair (102)
- Oxidative phosphorylation (99)
- RIG-I-like receptor signaling pathway (99)
- Tryptophan metabolism (99)
- Basal cell carcinoma (96)
- TGF-beta signaling pathway (93)
- Systemic lupus erythematosus (90)
- Drug metabolism - cytochrome P450 (84)
- Proteasome (84)
- Pyruvate metabolism (81)
- Arachidonic acid metabolism (78)
- Fatty acid metabolism (78)
- Metabolism of xenobiotics by cytochrome P450 (75)
- Calcium signaling pathway (74)
- Graft-versus-host disease (69)
- Propanoate metabolism (69)
- Type I diabetes mellitus (69)
- beta-Alanine metabolism (69)
- Fructose and mannose metabolism (63)
- Glutathione metabolism (63)
- Glycine (63)
- PPAR signaling pathway (63)
- serine and threonine metabolism (63)
- Butanoate metabolism (60)
- Citrate cycle (TCA cycle) (60)
- Inositol phosphate metabolism (60)
- Viral myocarditis (60)
- Antigen processing and presentation (57)
- Maturity onset diabetes of the young (57)
- Phosphatidylinositol signaling system (57)
- Cysteine and methionine metabolism (54)
- Retinol metabolism (54)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (51)
- Pentose phosphate pathway (51)
- Terpenoid backbone biosynthesis (51)
- Amino sugar and nucleotide sugar metabolism (48)
- Cytosolic DNA-sensing pathway (48)
- Linoleic acid metabolism (48)
- Lysine degradation (48)
- Regulation of autophagy (48)
- Neuroactive ligand-receptor interaction (45)
- Base excision repair (42)
- Synthesis and degradation of ketone bodies (42)
- Hypertrophic cardiomyopathy (HCM) (39)
- Vibrio cholerae infection (39)
- Allograft rejection (36)
- Ascorbate and aldarate metabolism (36)
- Autoimmune thyroid disease (33)
- Cardiac muscle contraction (33)
- Complement and coagulation cascades (33)
- Dilated cardiomyopathy (33)
- Galactose metabolism (33)
- Mismatch repair (33)
- Notch signaling pathway (33)
- RNA degradation (33)
- RNA polymerase (33)
- Caffeine metabolism (30)
- Drug metabolism - other enzymes (30)
- Lysosome (30)
- SNARE interactions in vesicular transport (30)
- Spliceosome (30)
- Starch and sucrose metabolism (30)
- DNA replication (27)
- Fatty acid elongation in mitochondria (24)
- Hedgehog signaling pathway (24)
- Histidine metabolism (24)
- N-Glycan biosynthesis (24)
- Nicotinate and nicotinamide metabolism (24)
- Non-homologous end-joining (24)
- One carbon pool by folate (24)
- Folate biosynthesis (21)
- Homologous recombination (21)
- Glycosaminoglycan degradation (18)
- Renin-angiotensin system (18)
- Sphingolipid metabolism (18)
- Alanine (15)
- Biosynthesis of unsaturated fatty acids (15)
- Glyoxylate and dicarboxylate metabolism (15)
- Other glycan degradation (15)
- Porphyrin and chlorophyll metabolism (15)
- Sulfur metabolism (15)
- aspartate and glutamate metabolism (15)
- Circadian rhythm - mammal (12)
- ECM-receptor interaction (12)
- Nitrogen metabolism (12)
- Pantothenate and CoA biosynthesis (12)
- Primary bile acid biosynthesis (12)
- Androgen and estrogen metabolism (9)
- Asthma (9)
- Basal transcription factors (9)
- Glycosphingolipid biosynthesis - ganglio series (9)
- Glycosphingolipid biosynthesis - lacto and neolacto series (9)
- Keratan sulfate biosynthesis (9)
- Methane metabolism (9)
- Selenoamino acid metabolism (9)
- Vitamin B6 metabolism (9)
- Fatty acid biosynthesis (6)
- Glycerophospholipid metabolism (6)
- Olfactory transduction (6)
- Phenylalanine metabolism (6)
- Steroid biosynthesis (6)
- Taurine and hypotaurine metabolism (6)
- leucine and isoleucine biosynthesis (6)
- Aminoacyl-tRNA biosynthesis (3)
- Limonene and pinene degradation (3)
- Pentose and glucuronate interconversions (3)