NAPSIN A (NAPSA) Mouse Monoclonal Antibody [Clone ID: OTI3A4]

CAT#: TA808773S

NAPSA mouse monoclonal antibody, clone OTI3A4

Product Images

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-NAPSA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA808773) (1:150)

• 

  Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-NAPSA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA808773) (1:150)

• 

  Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-NAPSA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA808773) (1:150)

• 

  Immunocytochemistry staining of A549 cells using anti-NAPSA mouse monoclonal antibody (TA808773). The right is HELA cells as negative control.

Specifications

Product Data

• Clone Name: OTI3A4
• Applications: IF, IHC
• Recommended Dilution: IHC 1:150
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 64-244 of human NAPSA(NP_004842) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42.7 kDa
• Gene Name: napsin A aspartic peptidase
• Database Link:
  NP_004842
  Entrez Gene 9476 Human
  UniProt ID O96009
• Background: The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq, Jul 2008]
• Synonyms: KAP; Kdap; NAP1; NAPA; SNAPA

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome