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Target Symbol
- MAP2K1 (36)
- MAP2K3 (30)
- UBE2G2 (27)
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- SNAP25 (21)
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- NDEL1 (12)
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- VWA5A (9)
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- ADH1B (6)
- ALDH1L1 (6)
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- C16ORF72 (6)
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Reactivities
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Clonalities
Knockout (KO) Validation
Families
- Druggable Genome (1299)
- Transmembrane (329)
- Transcription Factors (231)
- Protein Kinase (219)
- Secreted Protein (153)
- ES Cell Differentiation/IPS (132)
- Protease (105)
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- P450 (30)
- Adult stem cells (24)
- Embryonic stem cells (21)
- Ion Channels: Other (21)
- Phosphatase (21)
- Induced pluripotent stem cells (9)
- Cancer stem cells (6)
- Stem cell relevant signaling - DSL/Notch pathway (6)
- Stem cell relevant signaling - JAK/STAT signaling pathway (6)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (6)
- Stem cell relevant signaling - Wnt Signaling pathway (6)
- GPCR (3)
Pathways
- Metabolic pathways (315)
- Pathways in cancer (183)
- MAPK signaling pathway (150)
- Prostate cancer (135)
- Toll-like receptor signaling pathway (129)
- Fc epsilon RI signaling pathway (117)
- Progesterone-mediated oocyte maturation (117)
- Focal adhesion (114)
- Endometrial cancer (108)
- Gap junction (105)
- Insulin signaling pathway (105)
- Regulation of actin cytoskeleton (105)
- ErbB signaling pathway (102)
- Colorectal cancer (99)
- Pancreatic cancer (99)
- GnRH signaling pathway (90)
- Chronic myeloid leukemia (87)
- Non-small cell lung cancer (87)
- Acute myeloid leukemia (84)
- T cell receptor signaling pathway (84)
- Natural killer cell mediated cytotoxicity (81)
- Neurotrophin signaling pathway (81)
- Oocyte meiosis (81)
- B cell receptor signaling pathway (78)
- Bladder cancer (75)
- Fc gamma R-mediated phagocytosis (75)
- Melanoma (75)
- Glioma (72)
- Pathogenic Escherichia coli infection (72)
- Renal cell carcinoma (72)
- Thyroid cancer (72)
- VEGF signaling pathway (66)
- Cell cycle (63)
- Chemokine signaling pathway (60)
- Melanogenesis (60)
- Ubiquitin mediated proteolysis (57)
- Adherens junction (54)
- Jak-STAT signaling pathway (54)
- Amyotrophic lateral sclerosis (ALS) (51)
- Small cell lung cancer (51)
- Type II diabetes mellitus (51)
- Long-term depression (48)
- Long-term potentiation (48)
- Prion diseases (48)
- Vascular smooth muscle contraction (48)
- p53 signaling pathway (48)
- Apoptosis (45)
- Purine metabolism (42)
- Cell adhesion molecules (CAMs) (39)
- Dorso-ventral axis formation (39)
- Glycolysis / Gluconeogenesis (39)
- Proteasome (39)
- Alzheimer's disease (36)
- Pyrimidine metabolism (36)
- Wnt signaling pathway (36)
- Arginine and proline metabolism (33)
- Drug metabolism - cytochrome P450 (33)
- Leukocyte transendothelial migration (33)
- Parkinson's disease (33)
- Tyrosine metabolism (33)
- Huntington's disease (30)
- Metabolism of xenobiotics by cytochrome P450 (30)
- Axon guidance (27)
- Regulation of autophagy (27)
- Adipocytokine signaling pathway (24)
- Calcium signaling pathway (24)
- Endocytosis (24)
- Glycerolipid metabolism (24)
- Primary immunodeficiency (24)
- Retinol metabolism (24)
- SNARE interactions in vesicular transport (24)
- Tight junction (24)
- mTOR signaling pathway (24)
- Arachidonic acid metabolism (21)
- Basal cell carcinoma (21)
- Cytokine-cytokine receptor interaction (21)
- Inositol phosphate metabolism (21)
- Nucleotide excision repair (21)
- Systemic lupus erythematosus (21)
- TGF-beta signaling pathway (21)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (18)
- Epithelial cell signaling in Helicobacter pylori infection (18)
- Hematopoietic cell lineage (18)
- Maturity onset diabetes of the young (18)
- Phosphatidylinositol signaling system (18)
- RIG-I-like receptor signaling pathway (18)
- Terpenoid backbone biosynthesis (18)
- Viral myocarditis (18)
- Graft-versus-host disease (15)
- Lysosome (15)
- NOD-like receptor signaling pathway (15)
- Pyruvate metabolism (15)
- Type I diabetes mellitus (15)
- Allograft rejection (12)
- Base excision repair (12)
- Caffeine metabolism (12)
- Cytosolic DNA-sensing pathway (12)
- Glutathione metabolism (12)
- Glycosaminoglycan degradation (12)
- Hypertrophic cardiomyopathy (HCM) (12)
- Neuroactive ligand-receptor interaction (12)
- Tryptophan metabolism (12)
- Valine (12)
- Vibrio cholerae infection (12)
- beta-Alanine metabolism (12)
- leucine and isoleucine degradation (12)
- Amino sugar and nucleotide sugar metabolism (9)
- Antigen processing and presentation (9)
- Ascorbate and aldarate metabolism (9)
- Autoimmune thyroid disease (9)
- Butanoate metabolism (9)
- Cysteine and methionine metabolism (9)
- Dilated cardiomyopathy (9)
- Fatty acid metabolism (9)
- Fructose and mannose metabolism (9)
- Glycosphingolipid biosynthesis - lacto and neolacto series (9)
- Keratan sulfate biosynthesis (9)
- Linoleic acid metabolism (9)
- Oxidative phosphorylation (9)
- Pantothenate and CoA biosynthesis (9)
- Porphyrin and chlorophyll metabolism (9)
- Propanoate metabolism (9)
- RNA polymerase (9)
- Sphingolipid metabolism (9)
- Alanine (6)
- Citrate cycle (TCA cycle) (6)
- Complement and coagulation cascades (6)
- Drug metabolism - other enzymes (6)
- Fatty acid biosynthesis (6)
- Glycine (6)
- Histidine metabolism (6)
- N-Glycan biosynthesis (6)
- Nitrogen metabolism (6)
- One carbon pool by folate (6)
- Other glycan degradation (6)
- Phenylalanine metabolism (6)
- RNA degradation (6)
- Renin-angiotensin system (6)
- Spliceosome (6)
- Synthesis and degradation of ketone bodies (6)
- Vitamin B6 metabolism (6)
- aspartate and glutamate metabolism (6)
- serine and threonine metabolism (6)
- Asthma (3)
- Circadian rhythm - mammal (3)
- DNA replication (3)
- ECM-receptor interaction (3)
- Galactose metabolism (3)
- Glycosphingolipid biosynthesis - ganglio series (3)
- Glyoxylate and dicarboxylate metabolism (3)
- Hedgehog signaling pathway (3)
- Homologous recombination (3)
- Lysine degradation (3)
- Mismatch repair (3)
- Nicotinate and nicotinamide metabolism (3)
- Notch signaling pathway (3)
- Pentose phosphate pathway (3)
- Starch and sucrose metabolism (3)
- Steroid biosynthesis (3)
- Taurine and hypotaurine metabolism (3)