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Target Symbol
- MAP2K1 (70)
- MAP2K3 (55)
- NPR3 (45)
- RAB21 (40)
- DNM1L (35)
- ERBB2 (34)
- LTA4H (30)
- PIK3R5 (30)
- ACAA2 (25)
- ACAT2 (25)
- CTNNB1 (25)
- NME1 (25)
- OTC (25)
- TBC1D21 (25)
- ABCB1 (20)
- AGR2 (20)
- BCL2 (20)
- CYP2A6 (20)
- NIT2 (20)
- NRBP1 (20)
- OXSM (20)
- PCNA (20)
- PLK1 (20)
- PRKCE (20)
- SYT4 (20)
- MCM2 (18)
- ACSS2 (15)
- AKR1A1 (15)
- ASH2L (15)
- CDC123 (15)
- CDK15 (15)
- ESR1 (15)
- GPI (15)
- HOXC11 (15)
- ILVBL (15)
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- LIMK1 (15)
- MAPK13 (15)
- NOG (15)
- PDE4A (15)
- PIK3C2A (15)
- PPP5C (15)
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- SAMHD1 (15)
- TSC22D1 (15)
- GATA3 (13)
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- APP (11)
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- AMDHD1 (10)
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- FAF1 (10)
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- GABRA5 (10)
- GARS (10)
- H2AFY2 (10)
- HNRNPM (10)
- IQGAP1 (10)
- KRT8 (10)
- KYNU (10)
- LCMT1 (10)
- MAP2K4 (10)
- MME (10)
- NLN (10)
- NNMT (10)
- NOTCH1 (10)
- NR3C1 (10)
- OSGIN2 (10)
- PARN (10)
- PDE4B (10)
- PGAM2 (10)
- PMEL (10)
- PRKD2 (10)
- PSMA2 (10)
- RAB30 (10)
- RAD21 (10)
- RPL7A (10)
- SAE1 (10)
- SERPINB1 (10)
- SMS (10)
- SNX9 (10)
- SOCS3 (10)
- SOX17 (10)
- SRSF9 (10)
- STK39 (10)
- TLE1 (10)
- TMOD1 (10)
- TRIM45 (10)
- TUBAL3 (10)
- TYMS (10)
- TYRO3 (10)
Antibody Hosts
Conjugates
Knockout (KO) Validation
Families
- Druggable Genome (1890)
- Transcription Factors (490)
- Protein Kinase (417)
- Transmembrane (404)
- ES Cell Differentiation/IPS (192)
- Protease (173)
- Stem cell - Pluripotency (167)
- Secreted Protein (117)
- Adult stem cells (36)
- Stem cell relevant signaling - JAK/STAT signaling pathway (34)
- Nuclear Hormone Receptor (30)
- Cancer stem cells (23)
- P450 (20)
- Stem cell relevant signaling - DSL/Notch pathway (20)
- Embryonic stem cells (18)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (18)
- Phosphatase (15)
- Induced pluripotent stem cells (13)
- Ion Channels: Other (11)
- Ion Channels: Cys-loop Receptors (10)
- Stem cell relevant signaling - Wnt Signaling pathway (8)
- Ion Channels: Potassium (6)
- GPCR (5)
- Ion Channels: Transient receptor potential (2)
- Ion Channels: Calcium (1)
Pathways
- Metabolic pathways (426)
- Pathways in cancer (310)
- MAPK signaling pathway (244)
- Focal adhesion (233)
- Prostate cancer (227)
- Fc epsilon RI signaling pathway (220)
- Colorectal cancer (210)
- Toll-like receptor signaling pathway (206)
- ErbB signaling pathway (205)
- Progesterone-mediated oocyte maturation (197)
- Endometrial cancer (195)
- Fc gamma R-mediated phagocytosis (181)
- Neurotrophin signaling pathway (181)
- GnRH signaling pathway (174)
- Non-small cell lung cancer (167)
- Pancreatic cancer (163)
- Regulation of actin cytoskeleton (157)
- Renal cell carcinoma (152)
- Acute myeloid leukemia (148)
- B cell receptor signaling pathway (145)
- T cell receptor signaling pathway (145)
- Insulin signaling pathway (140)
- Chronic myeloid leukemia (138)
- Melanoma (138)
- VEGF signaling pathway (136)
- Bladder cancer (135)
- Glioma (133)
- Chemokine signaling pathway (126)
- Thyroid cancer (123)
- Natural killer cell mediated cytotoxicity (121)
- Melanogenesis (115)
- Amyotrophic lateral sclerosis (ALS) (101)
- Cell cycle (101)
- Oocyte meiosis (100)
- Prion diseases (98)
- Vascular smooth muscle contraction (96)
- Gap junction (94)
- Adherens junction (93)
- Leukocyte transendothelial migration (91)
- Purine metabolism (90)
- Wnt signaling pathway (89)
- Dorso-ventral axis formation (88)
- Small cell lung cancer (83)
- Endocytosis (81)
- Long-term potentiation (81)
- Long-term depression (80)
- Type II diabetes mellitus (76)
- Fatty acid metabolism (70)
- Valine (70)
- leucine and isoleucine degradation (70)
- Glycolysis / Gluconeogenesis (68)
- Jak-STAT signaling pathway (68)
- Apoptosis (65)
- mTOR signaling pathway (61)
- Epithelial cell signaling in Helicobacter pylori infection (59)
- Phosphatidylinositol signaling system (55)
- Tight junction (55)
- Ubiquitin mediated proteolysis (55)
- Arginine and proline metabolism (50)
- Propanoate metabolism (50)
- Pyrimidine metabolism (50)
- Calcium signaling pathway (48)
- Pathogenic Escherichia coli infection (46)
- Basal cell carcinoma (45)
- Pyruvate metabolism (45)
- Spliceosome (45)
- RNA degradation (43)
- Arachidonic acid metabolism (40)
- Butanoate metabolism (40)
- Tryptophan metabolism (40)
- DNA replication (38)
- Axon guidance (36)
- Base excision repair (36)
- Alzheimer's disease (35)
- Lysine degradation (35)
- Proteasome (35)
- Primary immunodeficiency (34)
- TGF-beta signaling pathway (33)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (31)
- Adipocytokine signaling pathway (30)
- Fatty acid elongation in mitochondria (30)
- Renin-angiotensin system (30)
- Terpenoid backbone biosynthesis (30)
- p53 signaling pathway (30)
- Nucleotide excision repair (29)
- Antigen processing and presentation (27)
- Drug metabolism - cytochrome P450 (25)
- Glutathione metabolism (25)
- Histidine metabolism (25)
- Inositol phosphate metabolism (25)
- Synthesis and degradation of ketone bodies (25)
- beta-Alanine metabolism (25)
- Mismatch repair (23)
- One carbon pool by folate (23)
- ABC transporters (20)
- Amino sugar and nucleotide sugar metabolism (20)
- Caffeine metabolism (20)
- Drug metabolism - other enzymes (20)
- Fatty acid biosynthesis (20)
- Glycerolipid metabolism (20)
- Hedgehog signaling pathway (20)
- Neuroactive ligand-receptor interaction (20)
- Notch signaling pathway (20)
- Oxidative phosphorylation (20)
- Pentose phosphate pathway (20)
- RIG-I-like receptor signaling pathway (20)
- Retinol metabolism (20)
- Starch and sucrose metabolism (20)
- Tyrosine metabolism (18)
- NOD-like receptor signaling pathway (17)
- Alanine (15)
- Nicotinate and nicotinamide metabolism (15)
- Vibrio cholerae infection (15)
- aspartate and glutamate metabolism (15)
- Cell adhesion molecules (CAMs) (13)
- Cytokine-cytokine receptor interaction (13)
- Parkinson's disease (11)
- Aminoacyl-tRNA biosynthesis (10)
- Androgen and estrogen metabolism (10)
- Cysteine and methionine metabolism (10)
- Hematopoietic cell lineage (10)
- Huntington's disease (10)
- Lysosome (10)
- Metabolism of xenobiotics by cytochrome P450 (10)
- PPAR signaling pathway (10)
- Ribosome (10)
- Selenoamino acid metabolism (10)
- Systemic lupus erythematosus (10)
- Cardiac muscle contraction (9)
- Dilated cardiomyopathy (9)
- Hypertrophic cardiomyopathy (HCM) (9)
- Ascorbate and aldarate metabolism (5)
- Citrate cycle (TCA cycle) (5)
- Complement and coagulation cascades (5)
- Folate biosynthesis (5)
- Fructose and mannose metabolism (5)
- Glycerophospholipid metabolism (5)
- Glyoxylate and dicarboxylate metabolism (5)
- Limonene and pinene degradation (5)
- Linoleic acid metabolism (5)
- Maturity onset diabetes of the young (5)
- Nitrogen metabolism (5)
- Porphyrin and chlorophyll metabolism (5)
- Protein export (5)
- Regulation of autophagy (5)
- SNARE interactions in vesicular transport (5)
- Steroid biosynthesis (5)
- Sulfur metabolism (5)
- Taurine and hypotaurine metabolism (5)
- Thiamine metabolism (5)
- Type I diabetes mellitus (5)
- Vitamin B6 metabolism (5)
- Viral myocarditis (1)