MSH2 Mouse Monoclonal Antibody [Clone ID: UMAB259]
Other products for "MSH2"
Specifications
Product Data | |
Clone Name | UMAB259 |
Applications | IHC |
Recommended Dilution | IHC 1:2400 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-304 of human MSH2 (NP_000242) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 104.6 kDa |
Gene Name | Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA. |
Database Link | |
Background | This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Synonyms | COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Colorectal cancer, Mismatch repair, Pathways in cancer |
Documents
Product Manuals |
FAQs |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM800149 | MSH2 mouse monoclonal antibody,clone UMAB259 |
USD 468.00 |
|
UM800149CF | Carrier-free (BSA/glycerol-free) MSH2 mouse monoclonal antibody,clone UMAB259 |
USD 528.00 |
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