MSH2 Mouse Monoclonal Antibody [Clone ID: UMAB259]

CAT#: UM800149

MSH2 mouse monoclonal antibody,clone UMAB259

Size: 30 ul 100 ul

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USD 468.00

In Stock*

Size
    • 100 ul

Other products for "MSH2"

Specifications

Product Data
Clone Name UMAB259
Applications IHC
Recommended Dilution IHC 1:2400
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-304 of human MSH2 (NP_000242) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 104.6 kDa
Gene Name Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA.
Background This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Synonyms COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Mismatch repair, Pathways in cancer

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